Lab Notes

How research peptides are tested, documented and stored

Plain-language guides to the analytical side of research peptides: what each line on a Certificate of Analysis means, how the methods behind it work, and how to check a report for yourself.

Documentation

How to read a peptide Certificate of Analysis

A field-by-field guide to a peptide Certificate of Analysis: lot number, HPLC purity, mass spec identity, net content, screening and verification.

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Testing methods

HPLC vs. mass spectrometry: purity and identity are different questions

HPLC measures how pure a peptide sample is; mass spectrometry confirms it is the right molecule. How each method works and how to read them together.

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Testing methods

Purity vs. net content: why they are two different numbers

Purity is a ratio and net content is an amount. Why lyophilized peptide powder is never all peptide, and how to read both figures on a COA.

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Testing methods

Endotoxin, sterility and heavy-metal testing, explained

Purity says nothing about contamination. How labs test peptides for endotoxin (LAL, USP <85>), sterility and heavy metals (ICP-MS), and how to read it.

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Storage

How to store lyophilized peptides

Lyophilized peptides last longest cold, dry and dark. Storage temperature, moisture, light and freeze-thaw, explained for sealed research material.

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Documentation

How to verify a peptide COA before you trust it

A COA is only useful if it is real and matches your vial. Six checks: lot number, lab verification key, date, size, what was run, and who commissioned it.

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Lumina Labs supplies research compounds for in vitro laboratory research use only. They are not intended for human or veterinary consumption, or to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA.

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